A patient is being treated for infertility. An examination reveals cervical mucus that is scant,thick, and sticky. The nurse suspects that the patient has been taking which medication?
a.Clomiphene (Clomid)
b.Estrogen
c.Follicle-stimulating hormone (FSH)
d.Progesterone
ANS: ABecause clomiphene has antiestrogenic actions, it can force the production of scant andviscous cervical mucus, which interferes with conception. Estrogen is given to create afavorable cervical mucous environment that is more hospitable to sperm. FSH andprogesterone do not alter cervical mucus in this way.DIF:Cognitive Level: ApplicationREF:Unfavorable Cervical Mucous | Clomiphene | Adverse EffectsTOP:Nursing Process: EvaluationMSC: NCLEX Client Needs Category: Physiologic Integrity: Pharmacologic and Parenteral Therapies
2.An infertile patient has received two 5-day courses of clomiphene (Clomid) to help herconceive. An ultrasound 1 week after the last dose reveals that follicular maturation hasoccurred without ovulation.
The nurse expects the next step for this patient to be:a.administration of human chorionic gonadotropin (hCG).b.an order for cabergoline to be given twice weekly.c.evaluation of ovarian and pituitary function.d.repeating clomiphene once daily for 5 days.
ANS: AWhen treatment with clomiphene has failed to produce ovulation after two courses, hCG isused to promote ovulation after follicular maturation has occurred. Cabergoline is used to treathyperprolactinemia when excessive prolactin secretion occurs. Ovarian and pituitary functionshould be evaluated before a patient begins treatment with clomiphene. If ovulation hadoccurred, another cycle of clomiphene would be indicated.DIF:Cognitive Level: ApplicationREF:Drugs Used to Treat Female Infertility | Drugs for Controlled Ovarian Stimulation | Clomiphene| Human Chorionic Gonadotropin | Therapeutic Use | Dopamine Agonists for Hyperprolactinemia |CabergolineTOP:Nursing Process: EvaluationMSC: NCLEX Client Needs Category: Physiologic Integrity: Pharmacologic and Parenteral Therapies
3.A patient who has endometriosis has been unable to conceive.
She asks the nurse aboutmedications to treat the condition. What will the nurse tell the patient?
a.Combination oral contraceptives are effective for improving fertility.
b.Gonadotropin-releasing hormone agonists are used for long-term treatment.
c.Nonsteroidal anti-inflammatory drugs are second-line agents for treating pain.
d.Pharmacologic agents used to treat endometriosis do not enhance fertility.